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IL-13 Antibody (13A) Summary

    Immunogen
    The immunogen for this antibody was IL13.
    Isotype
    IgG1 Kappa
    Clonality
    Monoclonal
    Host
    Rat
    Gene
    IL13
    Purity
    Protein A or G purified
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Applications/Dilutions

    Dilutions
        ELISA
        Flow Cytometry
    Application Notes
    The eBio13A antibody has been tested as the capture antibody in a sandwich ELISA (and ELISPOT) for analysis of mouse IL-13, in combination with the biotinylated eBio1316H antibody for detection (13-7135) and recombinant mouse IL-13 (14-8131) as the standard. A suitable range of concentrations of this antibody for ELISA capture is 1.0 – 4.0 ug/ml. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 1000 pg/ml – 8.0 pg/ml should be included in each ELISA plate.

    The Functional Grade Purified eBio1316H antibody (16-7135) is recommended for in vitro blocking studies.

Reactivity Notes

This antibody is reactive to Mouse.

Packaging, Storage & Formulations

    Storage
    Store at 4C. Do not freeze.
    Buffer
    Aqueous, may contain carrier protein/stabilizer.
    Preservative
    0.09% Sodium Azide
    Concentration
    0.5 mg/ml
    Purity
    Protein A or G purified

Alternate Names for IL-13 Antibody (13A)

      ALRHMGC116789
      BHR1interleukin-13
      IL13
      IL-13
      IL-13MGC116788
      interleukin 13
      MGC116786
      NC30
      P600

Background

The 13A antibody reacts with mouse IL-13. IL-13 is a cytokine produced mainly by Th2 cells, but also by antigen-primed CD8 T cells. IL-13 has a strong involvement in allergic inflammation and parasitic clearing and in cancer models has been shown to have either inhibitory or stimulatory activity depending on the tumor. In humans, IL-13 is found to play a role in isotype switching in B cells. IL-13 is implicating in down modulating macrophage activity, through the reduction of pro-inflammatory cytokines (IL-1, IL-6, IL-8, IL-10, IL-12)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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