IFN-beta Antibody [Unconjugated] Summary
Chinese hamster ovary cell line CHO-derived recombinant rat IFN-beta
Neutralizes both natural and recombinant rat interferon beta. Cross-reactivity with human interferon beta has not been tested.
N/A
IgG
Polyclonal
Rabbit
IFNB1
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
Applications/Dilutions
- Neutralization
Packaging, Storage & Formulations
Upon receipt, this product is stable at 4°C until the expiration date listed above. After reconstitution, the contents can be safely stored at 4°C for one month or at -20°C for one year for retention of full activity.When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Add 0.02% sodium azide to prevent bacterial growth.
0.5 ml Phosphate-buffered saline (PBS) + 125 mM trehalose prior to lyophilization.
No Preservative
Dissolve contents of the vial by injection of 0.5 ml sterile distilled water.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for IFN-beta Antibody [Unconjugated]
- Fibroblast interferon
- IFBIFNB
- IFF
- IFNB1
- IFNbeta
- IFN-beta
- interferon beta
- interferon, beta 1, fibroblast
- MGC96956
Background
Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets : GABA Receptor inhibitors