ijo.2016.96

ICAM-2/CD102 Antibody (3C4) [FITC] Summary

    Immunogen
    COS cells transfected with mouse ICAM-2 cDNA and BW5147 AKR/J mouse thymoma cell line
    Isotype
    IgG2a Kappa
    Clonality
    Monoclonal
    Host
    Rat
    Gene
    ICAM2
    Purity
    Protein A or G purified
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Applications/Dilutions

    Dilutions
        Flow Cytometry 1 ug/10^6 cells
        Immunohistochemistry 1:10-1:500
        Immunohistochemistry-Frozen 1:10-1:500
        Immunoprecipitation 1:10-1:500
        In vitro assay
        Immunocytochemistry

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

    Storage
    Store at 4C. Do not freeze.
    Buffer
    PBS
    Preservative
    0.05% Sodium Azide
    Purity
    Protein A or G purified

Notes

Protect conjugated forms from light.

Alternate Names for ICAM-2/CD102 Antibody (3C4) [FITC]

      CD102 antigen
      CD102
      ICAM2
      ICAM-2
      intercellular adhesion molecule 2

Background

The 3C4 (mIC2/4) monoclonal antibody reacts with mouse ICAM-2 (CD102) cell surface glycoprotein, a ligand for the leucocyte integrin CD11a/CD18 (LFA-1).1 CD102 is constitutively expressed on T cells, B cells, and at high levels on vascular endothelial cells. (2) It is also expressed on a variety of leukocyte cell lines. (1) The 3C4 antibody blocks the interaction between ICAM-2 and LFA-1. (1)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : Urotensin Receptor inhibitors

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