2047-2994-4-S1-O13

Human Resistin ELISA Kit (Colorimetric) Summary

    Specificity
    The interference of circulating factors of the immune system was evaluated by spiking these proteins at physiologically relevant concentrations into a human Resistin positive serum. There was no crossreactivity detected.
    Standard Curve Range
    31 – 2,000 pg/mL
    Sensitivity
    3.1 pg/mL
    Assay Type
    Sandwich ELISA
    Inter-Assay
    8.1%
    Intra-Assay
    5.1%
    Sample Volume
    50 uL
    Kit Type
    ELISA Kit (Colorimetric)
    Gene
    RETN

Applications/Dilutions

    Application Notes
    This kit is an enzyme-linked immunosorbent assay for quantitative detection.

Reactivity Notes

Human

Packaging, Storage & Formulations

    Storage
    Storage of components varies. See protocol for specific instructions.

Kit Components

Components
      Aluminium pouch(es) with a Microwell Plate coated with polyclonal antibody to human Resistin
      Adhesive Films
      Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
      Human Resistin Standard lyophilized, 4000 pg/ml upon reconstitution
      Biotin-Conjugate anti-human Resistin polyclonal antibody
      Stop Solution (1M Phosphoric acid)
      Substrate Solution (tetramethyl-benzidine)
      Streptavidin-HRP
      Wash Buffer Concentrate 20x (PBS with 1% Tween 20)

Alternate Names for Human Resistin ELISA Kit (Colorimetric)

      Adipose tissue-specific secretory factor
      ADSF
      ADSFMGC126609
      C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich proteinprecursor 1
      C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein
      Cysteine-rich secreted protein A12-alpha-like 2
      Cysteine-rich secreted protein FIZZ3
      FIZZ3
      FIZZ3MGC126603
      found in inflammatory zone 3
      HXCP1
      Resistin
      RETN
      RETN1
      RSTNXCP1

Background

Resistin is a hormone secreted by adipose tissue. The length of the resistin pre-peptide in human is 108 aminoacids; the molecular weight is ~12.5 kDa. Resistin was originally found to be produced and released from adipose tissue to serve endocrine functions likely involved in insulin resistance. This idea primarily stems from studies demonstrating that serum resistin levels increase with obesity in several model systems. Since these observations, further research has linked resistin to other physiological systems such as inflammation and energy homeostasis. Current research is proposing to link resistin to inflammation and energy homeostasis, including its alleged role in insulin resistance in obese subjects.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Arg-Gly-Asp-Ser

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