s12885-015-1993-3

Human CD117/c-kit ELISA Kit (Colorimetric) Summary

    Description
    Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, c-Kit can activate several signaling pathways.. Novus c-Kit ELISA kit is a sandwich ELISA assay for the quantitative measurement of human c-Kit in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of c-Kit captured from the samples.
    Standard Curve Range
    0.781-50 ng/ml
    Sensitivity
    < 0.469 ng/ml
    Assay Type
    Sandwich ELISA
    Sample Volume
    0.1 ml
    Kit Type
    ELISA Kit (Colorimetric)
    Gene
    KIT

Applications/Dilutions

    Application Notes
    Detection Method: Absorbance (450 nm). Quantitative measurement of c-Kit in serum, plasma, tissue homogenates, culture supernatants and other biological fluids.

Packaging, Storage & Formulations

    Storage
    Store at -20 °C.

Kit Components

Components
      TMB substrate
      Wash buffer (25X)
      Stop Solution
      Sample / Standard dilution buffer
      SABC dilution buffer
      Biotin- detection antibody (Concentrated)
      Antibody dilution buffer
      HRP-Streptavidin Conjugate (SABC)
      Lyophilized Standard
      Microplate: 96 wells
      Plate sealers

Alternate Names for Human CD117/c-kit ELISA Kit (Colorimetric)

      CD117 antigen
      CD117
      ckit
      c-kit
      EC 2.7.10
      EC 2.7.10.1
      KIT
      PBT
      piebald trait
      Proto-oncogene c-Kit
      proto-oncogene tyrosine-protein kinase Kit
      SCF R
      SCFR
      SCFRmast/stem cell growth factor receptor
      soluble KIT variant 1
      Tyrosine-protein kinase Kit
      v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
      v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Brigatinib

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