journal.pbio.1000431

Human Annexin V ELISA Kit (Colorimetric) Summary

    Specificity
    The interference of circulating factors of the immune systeme was evaluated by spiking these proteins at physiologically relevant concentrations into a human Annexin V positive serum. There was no crossreactivity detected, notably not with Annexin VIII (Vac beta).
    Standard Curve Range
    0.78 – 50 ng/mL
    Sensitivity
    0.33 ng/mL
    Assay Type
    Sandwich ELISA
    Inter-Assay
    11.00%
    Intra-Assay
    10%
    Spike Recovery
    The overall mean recovery was 85%. Please see protocol for more specific Spike Recovery details.
    Sample Volume
    50 uL
    Kit Type
    ELISA Kit (Colorimetric)
    Gene
    ANXA5

Applications/Dilutions

    Application Notes
    The human Annexin V ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of human Annexin V.

Reactivity Notes

Human

Packaging, Storage & Formulations

    Storage
    Storage of components varies. See protocol for specific instructions.

Kit Components

Components
      Streptavidin-HRP
      Substrate Solution (tetramethyl-benzidine)
      Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
      Stop Solution (1M Phosphoric acid)
      Sample Diluent
      Human Annexin V Standard lyophilized, 100 ng/ml upon reconstitution
      Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human Annexin V
      Adhesive Films
      Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
      Biotin-Conjugate anti-human Annexin V monoclonal antibody

Alternate Names for Human Annexin V ELISA Kit (Colorimetric)

      Anchorin CII
      annexin A5
      Annexin V
      annexin-5
      ANX5
      ANXA5
      ANXV
      Calphobindin I
      Endonexin II
      ENX2CBP-I
      Lipocortin V
      PAP-I
      Placental anticoagulant protein 4
      Placental anticoagulant protein I
      PP4
      Thromboplastin inhibitor
      VAC-alpha
      Vascular anticoagulant-alpha

Background

Annexin V will bind to the phosphatidylserine-exposing apoptotic cell and can inhibit the procoagulant and proinflammatory activities of the dying cell. Total endogenous annexin V can be detected with the present ELISA which will offer further insights in the pathophysiological role of Annexin V.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

PI-3066

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