Histone H4 [Dimethyl Lys20] Antibody (2B8) Summary
Made to Human HISTONE H4
Dimethyl Lys20
Recognizes histone H4 when it is dimethylated at K20. It does not bind to non-methylated H4. K20 is the only site on histone H4 methylated in vivo. This has been reported for use in chromatin immunoprecipitation assay(1).
IgG2a
Monoclonal
Rat
HIST4H4
Protein G purified
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Applications/Dilutions
- Western Blot 1:100-1:1000
- Immunoprecipitation 1:10-1:500
Reactivity Notes
Reacts with Human.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.4)
0.09% Sodium Azide
1.0 mg/ml
Protein G purified
Alternate Names for Histone H4 [Dimethyl Lys20] Antibody (2B8)
- H4
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4/p
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- H4K20Me2
- H4M
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST4H4
- histone 4, H4
- Histone Cluster 1 H4
- Histone Cluster 1 H4i
- Histone Cluster 4 H4
- histone cluster 4, H4
- Histone H4
- MGC24116
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.