j.ces.2015.06.066

Hemoglobin gamma A Antibody (1G8) Summary

    Immunogen
    HBG1 (AAH10913, 1 a.a. – 147 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAVMGNPKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVASALSSRYH
    Specificity
    HBG1 – hemoglobin, gamma A (1G8)
    Isotype
    IgG2a Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    HBG1
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        ELISA
    Application Notes
    It has been used for ELISA.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    PBS (pH 7.4)
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Hemoglobin gamma A Antibody (1G8)

      A-gamma globin
      gamma A hemoglobin
      gamma globin
      gamma-1-globin
      Hb F Agamma
      HBGA
      HBGR
      Hemoglobin gamma-1 chain
      Hemoglobin gamma-A chain
      hemoglobin subunit gamma-1
      hemoglobin, gamma A
      hemoglobin, gamma, regulator of
      HSGGL1

Background

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5-epsilon — gamma-G — gamma-A — delta — beta–3. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

RG7389

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