journal.pone.0143448

HINT1 Antibody Summary

    Immunogen
    HINT1 (AAH01287, 1 a.a. ~ 126 a.a) partial recombinant protein.
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Mouse
    Gene
    HINT1
    Purity
    Unpurified
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Applications/Dilutions

    Dilutions
        Western Blot
        ELISA
    Application Notes
    Useful for Western Blot and ELISA.

Reactivity Notes

Human.

Packaging, Storage & Formulations

    Storage
    Store at -20C. Avoid freeze-thaw cycles.
    Buffer
    Whole antisera with PBS with 50 % Glycerol
    Preservative
    No Preservative
    Purity
    Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HINT1 Antibody

      Adenosine 5-monophosphoramidase
      EC 3.-
      HINT
      histidine triad nucleotide binding protein 1
      histidine triad nucleotide-binding protein 1
      histidine triad nucleotide-binding protein
      PKCI1
      PKCI-1FLJ30414
      PRKCNH1FLJ32340
      Protein kinase C inhibitor 1
      Protein kinase C-interacting protein 1

Background

HINT1, also known as Histidine triad nucleotide-binding protein 1, is a member of superfamily named for a near C-terminal HXHXHXX motif (H:Histidine, X:a hydrophobic amino acid) positioned at the alpha-phosphate of nucleotide substrates. This protein hydrolyzes adenosine 5-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2. Although it was originally thought to be a protein kinase C inhibitor and act as a haplod-insufficient tumor suppressor including spontaneous tumor formation in Hint+/- and Hint-/-, its actual physiologic function is not known. Recombinant human HINT1 protein was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

LY2835220

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