GnRHR Antibody Summary
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GNRHR.
Secreted
Human GNRHR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Porcine (90%), Bovine (90%), Equine (90%), Primate (90%), Monkey (95%), Canine (95%). Backed by our 100% Guarantee.
IgG
Polyclonal
Rabbit
GNRHR
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
Applications/Dilutions
- Immunohistochemistry-Paraffin 1 – 2 ug/ml
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gibbon (100%), Gorilla (95%), Elephant (95%), Panda (95%), Marmoset (90%), Mouse (85%), Rat (85%), Sheep (85%), Bat (85%), Rabbit (85%), Opossum (85%), Hamster (80%), Guinea Pig (80%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS
0.1% Sodium Azide
1.0 mg/ml
Immunogen affinity purified
Alternate Names for GnRHR Antibody
- GnRH receptor
- GnRHR
- GnRH-R
- GNRHR1
- gonadotropin-releasing hormone (type 1) receptor 1
- gonadotropin-releasing hormone receptor
- GRHR
- HH7
- leutinizing-releasing hormone receptor
- LHRHR
- LHRHRleutinizing hormone releasing horomone receptor
- LRHR
- luliberin receptor
- Luliberin
- type I GnRH receptor
Background
GnRHR is a Releasing-Hormone Receptor activated by gonadotropin-releasing hormone (GnRH). This receptor plays a major role in the regulation of reproductive functions. It modulates the synthesis and secretion of gonadotropin hormones such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary. In turn, LH and FSH regulate the release of steroid hormones from the gonads. Mutations in GnRHR have been linked to hypogonadotropic hypogonadism, a condition characterized by absence or delayed puberty and retarded bone maturation. GnRHR has been reported to be expressed mostly in the pituitary gonadotropes and in reproductive organs, including ovary, placenta, prostate, testis, and uterus. It is also expressed in breast, heart, kidney, liver, skeletal muscle, and thymus. No human ESTs have been isolated for this receptor.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.