prp2.311

Glycophorin C Antibody (BRIC10) Summary

    Immunogen
    Human erythrocytes
    Specificity
    NB100-66522 recognizes an epitope in the N-terminal region of CD236, also known as glycophorin C (GPC). CD236 is an integral membrane protein which carries the Gerbich blood group antigens. Expression of CD236 is not restricted to erythroid cells, but is broadly distributed in both erythroid and non-erythroid tissues.
    Isotype
    IgG1
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    GYPC
    Purity
    Protein G purified
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Applications/Dilutions

    Dilutions
        Western Blot 1:100-1:2000
        Flow Cytometry 1:10-1:1000

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    Tris-Glycine (pH 7.4)
    Preservative
    0.09% Sodium Azide
    Concentration
    1.0 mg/ml
    Purity
    Protein G purified

Alternate Names for Glycophorin C Antibody (BRIC10)

      CD236 antigen
      CD236
      CD236R
      GE
      GLPC
      glycoconnectin
      glycophorin C (Gerbich blood group)
      glycophorin-C
      glycophorin-D
      Glycoprotein beta
      GPCMGC126191
      GPD
      GYPD
      MGC117309
      MGC126192
      PAS-2
      PAS-2
      Sialoglycoprotein D

Background

CD236 is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. CD236 (Glycophorin C) plays an important role in regulating the stability of red cells. Expression of Glycophorin C is not restricted to erythroid cells but is broadly distributed in both erythroid and non erythroid tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

3-Methyladenine

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