GUCY2D Antibody Summary
GUCY2D (NP_000171, 521 a.a. – 630 a.a.) partial recombinant protein with GST tag. RKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFPGDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDL
GUCY2D – guanylate cyclase 2D, membrane (retina-specific)
IgG
Polyclonal
Mouse
GUCY2D
Unpurified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
Applications/Dilutions
- Western Blot
- ELISA
The quality control of this antibody is limited to WB on the immunizing protein. It has been used for ELISA. Abnovas recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Whole antisera with 50% Glycerol
No Preservative
Unpurified
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for GUCY2D Antibody
- CORD6cone rod dystrophy 5/6
- CYGD
- EC 4.6.1
- guanylate cyclase 2D, membrane (retina-specific)
- Guanylate cyclase 2D, retinal
- GUC1A4
- GUC2DCORD5
- LCA
- LCA1RCD2
- retGC
- RETGC1
- RETGC-1EC 4.6.1.2
- retinal guanylyl cyclase 1
- Rod outer segment membrane guanylate cyclase
- ROSGC
- ROS-GC
- ROS-GC1
Background
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.