jmir.4817

GPR50 Antibody Summary

    Immunogen
    Synthetic 20 amino acid peptide from C-terminus of human GPR50.
    Localization
    Cell Membrane
    Specificity
    Human GPR50. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Predicted Species
    Monkey (95%). Backed by our 100% Guarantee.
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    GPR50
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        Immunohistochemistry-Paraffin 3 – 28 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Marmoset (90%), Gibbon (85%).

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    PBS
    Preservative
    0.1% Sodium Azide
    Concentration
    1.0 mg/ml
    Purity
    Immunogen affinity purified

Alternate Names for GPR50 Antibody

      G protein-coupled receptor 50H9Mel1c
      GPR50
      H9
      melatonin-related receptor
      MGC125342
      MTR1L

Background

Melatonin-related receptor is an Orphan-A GPCR with an unknown ligand. The receptor is related to high-affinity melatonin receptors, yet it is unable to bind the melatonin hormone. Melatonin-related receptor expression has been documented from human CNS tissues, specifically in hypothalamus and pituitary, but not in human peripheral tissues. In animals, expression has also been seen in the CNS, and peripheral tissues including adrenal, heart, kidney, lung, skin, intestine, stomach, and testis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

CHR-6495

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