ecancer.2015.602

GPR18 Antibody Summary

    Immunogen
    Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human GPR18.
    Epitope
    3rd cytoplasmic domain of human
    Specificity
    Human GPR18. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Predicted Species
    Primate (94%), Equine (94%), Monkey (100%), Bat (94%). Backed by our 100% Guarantee.
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    GPR18
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        ELISA 1:100 – 1:2000
        Immunohistochemistry-Paraffin 5 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%), Elephant (94%), Bovine (89%), Rabbit (89%), Porcine (89%), Mouse (83%), Rat (83%), Pufferfish (83%).

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    PBS
    Preservative
    0.1% Sodium Azide
    Concentration
    1.0 mg/ml
    Purity
    Immunogen affinity purified

Alternate Names for GPR18 Antibody

      G protein-coupled receptor 18
      GPCRW
      GPR18
      G-protein coupled receptor 18
      NAGly Receptor
      N-arachidonyl glycine receptor

Background

G protein coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR18 is a member of this family and has been reported to be expressed at high levels in testis and spleen and at lower levels in other tissues associated with endocrine and immunologic/hematologic functions. It is thought to be a receptor for N arachidonyl glycine. It may contribute to regulation of the immune system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

VGX-1028

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