journal.pone.0053435

Follistatin-related Gene Protein/FLRG/Fstl3 Antibody (RM0080-7D11) Summary

    Immunogen
    Mouse recombinant FLRG
    Specificity
    This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse recombinant FLGR.
    Isotype
    IgG2
    Clonality
    Monoclonal
    Host
    Rat
    Gene
    FSTL3
    Purity
    Protein G purified
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Applications/Dilutions

    Dilutions
        Western Blot 1:500-1:1000

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    A 0.2 um filtered solution in PBS
    Preservative
    No Preservative
    Concentration
    LYOPH
    Purity
    Protein G purified
    Reconstitution Instructions
    Reconstitute with 0.2 ml sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for Follistatin-related Gene Protein/FLRG/Fstl3 Antibody (RM0080-7D11)

      FLRG
      FLRGFSRP
      follistatin-like 3 (secreted glycoprotein)
      Follistatin-like 3
      Follistatin-like protein 3
      Follistatin-related gene protein
      follistatin-related protein 3
      FSTL3

Background

FSTL3, follistatin-like 3, is a secreted glycoprotein of the follistatin-module-protein family. FSTL3 is expressed in the placenta and may play a role in regulating the extracellular matrix of the placenta. FSTL3 is a binding protein for activin and BMP2 and thought to regulate activin and myostatin during normal adult metabolic homeostasis. FSTL3 may also contribute to bone formation by inhibiting osteoclast differentiation from hematopoietic precursors. A chromosomal aberration involving FSTL3 is found in a case of B-cell chronic lymphocytic leukemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Siponimod

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