srep17657

Flamingo homolog 1/CELSR3 Antibody Summary

    Immunogen
    Synthetic 15 amino acid peptide from N-terminal extracellular domain of human CELSR3.
    Specificity
    Human CELSR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Predicted Species
    Primate (93%), Monkey (94%). Backed by our 100% Guarantee.
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    CELSR3
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (93%).

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    PBS
    Preservative
    0.1% Sodium Azide
    Concentration
    1.0 mg/ml
    Purity
    Immunogen affinity purified

Alternate Names for Flamingo homolog 1/CELSR3 Antibody

      Cadherin family member 11
      cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
      CDHF11
      CDHF11RESDA1
      CELSR3
      EGFL1
      EGFL1cadherin EGF LAG seven-pass G-type receptor 3
      EGF-like protein 1
      EGF-like-domain, multiple 1
      epidermal growth factor-like 1
      Epidermal growth factor-like protein 1
      Flamingo homolog 1
      FMI1anchor protein
      HFMI1
      KIAA0812
      MEGF2
      MEGF2cadherin EGF LAG seven-pass G-type receptor 3, flamingo (Drosophila) homolog
      multiple EGF-like domains 2
      Multiple EGF-like domains protein 2
      Multiple epidermal growth factor-like domains protein 2
      RESDA1

Background

CELSR3 is an Orphan-U GPCR with an unknown ligand. In mouse, this gene is expressed during development at sites of active neurogenesis and in adult mice and rats in brain, spinal cord, dorsal root ganglion, and eye. ESTs have been isolated from human B-cell/lung/testis, blood, brain, colon, heart/melanocyte/uterus, lung, nerve, and placenta libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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