j.ophtha.2015.11.023

Ferritin Light Chain Antibody (7A4) Summary

    Immunogen
    Human Ferritin Light Chain from liver.
    Marker
    Microglia Marker
    Specificity
    NB100-62561 is specific for human Ferritin Light Chain.
    Isotype
    IgG3
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    FTL
    Purity
    Protein G purified
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Applications/Dilutions

    Dilutions
        ELISA 1:100-1:2000
    Positive Control Ferritin Light Chain Lysate (NBL1-10851)

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    No buffer
    Preservative
    0.09% Sodium Azide
    Concentration
    1.0 mg/ml
    Purity
    Protein G purified

Alternate Names for Ferritin Light Chain Antibody (7A4)

      Ferritin L subunit
      ferritin L-chain
      ferritin light chain
      ferritin light polypeptide-like 3
      ferritin, light polypeptide
      MGC71996
      NBIA3

Background

This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

ENMD-2084

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