FGF R2 Antibody – Pre-diluted Summary
A synthetic peptide from aa 362-374 of human FGFR-2 protein
This product is specific for FGFR-2
IgG
Polyclonal
Rabbit
FGFR2
Immunogen affinity purified
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Applications/Dilutions
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Paraffin Neat
IHC-P: Use at a dilution of 1/1. Perform enzymatic antigen retrieval before commencing with IHC staining protocol, by boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.
Reactivity Notes
This product is specific for Human.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Prediluted antibody
No Preservative
Immunogen affinity purified
Alternate Names for FGF R2 Antibody – Pre-diluted
- BBDS
- BEK
- BFR-1
- CD332 antigen
- CD332
- CEK3
- CFD1
- craniofacial dysostosis 1
- EC 2.7.10
- EC 2.7.10.1
- ECT1
- FGF R2
- FGFR2
- fibroblast growth factor receptor 2
- FLJ98662
- Jackson-Weiss syndrome
- JWS
- Keratinocyte growth factor receptorreceptor like 14
- KGFR
- KSAM
- K-sam
- soluble FGFR4 variant 4
- TK14
- TK25
Background
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.