FAM3C Antibody (Delphy-1) Summary
Recombinant human ILEI (aa 42-227).
IgG2a
Monoclonal
Mouse
FAM3C
Protein G purified
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Applications/Dilutions
- Western Blot 1:1000
- ELISA 1:100-1:2000
- Immunoprecipitation 1:100
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS
0.02% Sodium Azide
1.0 mg/ml
Protein G purified
Alternate Names for FAM3C Antibody (Delphy-1)
- D6WSU176e
- FAM3C
- family with sequence similarity 3, member C
- GS3876
- ILEI
- ILEIInterleukin-like EMT inducer
- predicted osteoblast protein
Background
In 2006, T. Waerner, et al. characterized ILEI as a key player in both epithelial to mesenchymal transition and late-stage carcinoma progression. EMT is a process that involves changes in gene expression, cytoskeleton organization, cell adhesion, and extracellular matrix composition. This process is important during tissue formation and organogenesis, but also during cancer progression, metastasis and chronic inflammation. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.