journal.pgen.1005505

Erbin Antibody (10D2) Summary

    Immunogen
    ERBB2IP (NP_061165, 1272 a.a. ~ 1372 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.QGHELAKQEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIEHGQAVSLLKTFQNTVELIIVREVSS
    Specificity
    ERBB2IP – erbb2 interacting protein (10D2)
    Isotype
    IgG2a Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    ERBB2IP
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        Western Blot 1:500
        ELISA
    Application Notes
    Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    PBS (pH 7.4)
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Erbin Antibody (10D2)

      Densin-180-like protein
      erbb2 interacting protein
      Erbb2-interacting proteinErbin
      ERBB2IP
      Erbin
      ERBINLAP2protein LAP2
      KIAA1225

Background

This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

GSK0662

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