ErbB4/Her4 Antibody Summary
Synthetic 19 amino acid peptide from internal region of human ERBB4.
Human
Internal domain of human.
Human ERBB4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Opossum (100%), Bat (95%), Primate (100%), Equine (95%), Monkey (95%). Backed by our 100% Guarantee.
IgG
Polyclonal
Rabbit
ERBB4
Immunogen affinity purified
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Applications/Dilutions
- Immunohistochemistry-Paraffin 30 ug/ml
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Panda (100%), Mouse (89%), Rat (89%), Hamster (89%), Porcine (89%), Chicken (89%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS
0.1% Sodium Azide
1.0 mg/ml
Immunogen affinity purified
Alternate Names for ErbB4/Her4 Antibody
- avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4
- EC 2.7.10
- EC 2.7.10.1
- ErbB4
- HER4
- HER4MGC138404
- p180erbB4
- Proto-oncogene-like protein c-ErbB-4
- receptor tyrosine-protein kinase erbB-4
- Tyrosine kinase-type cell surface receptor HER4
- v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4
- v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
Background
ERBB-4 receptor tyrosine kinase is activated by neuregulins, nrg- 2, nrg-3, heparin-binding egf-like growth factor, betacellulin and ntak to regulate cell proliferation and differentiation. Several isoforms of the ERBB-4 receptor tyrosine kinase have been identified and differ functionally in their response to phorbol ester: they represent cleavable and noncleavable forms of the receptor. These isoforms are differentially expressed in tissues.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.