E6AP/UBE3A Antibody (3E5.) Summary
UBE3A (AAH09271, 51 a.a. – 150 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ETFQQLITYKVISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELTLQELLGEERRNKKGPRVDPLETELGVKTLDCR
UBE3A – ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) (3E5)
IgG2a Kappa
Monoclonal
Mouse
UBE3A
IgG purified
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Applications/Dilutions
- Western Blot
- ELISA
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
IgG purified
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for E6AP/UBE3A Antibody (3E5.)
- ANCR
- ANCREPVE6AP
- AS
- CTCL tumor antigen se37-2
- E6AP ubiquitin-protein ligase
- E6AP
- E6-AP
- EC 6.3.2.-
- EPVE6AP
- FLJ26981
- HPVE6A
- human papilloma virus E6-associated protein
- Human papillomavirus E6-associated protein
- Oncogenic protein-associated protein E6-AP
- Renal carcinoma antigen NY-REN-54
- UBE3A
- ubiquitin protein ligase E3A
- ubiquitin-protein ligase E3A
Background
This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets :　Others inhibitors