Dopamine D5 R/DRD5 Antibody – Pre-diluted Summary
Synthetic peptide corresponding to aa 459-477 of human D5DR.
This product is specific for D5DR
IgG
Polyclonal
Rabbit
DRD5
Immunogen affinity purified
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Applications/Dilutions
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Paraffin Neat
IHC-P: ready-to-use for 10 min at RT. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.
Reactivity Notes
This product is specific for Human.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Prediluted antibody
No Preservative
Immunogen affinity purified
Alternate Names for Dopamine D5 R/DRD5 Antibody – Pre-diluted
- D(1B) dopamine receptor
- D(5) dopamine receptor
- D1beta dopamine receptor
- DBDR
- Dopamine D5 R
- Dopamine D5 receptor
- Dopamine D5R
- dopamine receptor D1B
- dopamine receptor D5
- DRD1B
- DRD1BDBDR
- DRD1L2
- DRD1L2MGC10601
- DRD5
Background
The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin, and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Beta-adrenergic receptor bound to adrenaline activates adenylyl cyclase, while alpha 2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes; D1 and D2, which differ in their functional characteristics. D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.