j.ajodo.2015.05.034

Dkk-1 Antibody Summary

    Immunogen
    Synthetic 15 amino acid peptide from 1st cytoplasmic domain of human DKK1.
    Epitope
    1st cytoplasmic domain of human
    Localization
    Secreted
    Specificity
    Human DKK1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Predicted Species
    Monkey (93%). Backed by our 100% Guarantee.
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    DKK1
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        Immunohistochemistry-Paraffin 10 ug/ml
    Positive Control Dkk-1 Lysate (NBL1-09901)

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (80%).

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    PBS
    Preservative
    0.1% Sodium Azide
    Concentration
    1.0 mg/ml
    Purity
    Immunogen affinity purified

Alternate Names for Dkk-1 Antibody

      dickkopf (Xenopus laevis) homolog 1
      dickkopf homolog 1 (Xenopus laevis)
      dickkopf related protein-1
      Dickkopf-1
      dickkopf-related protein 1
      Dkk1
      Dkk-1
      hDkk-1
      SKdickkopf-1 like

Background

DKK1 is an inhibitor of the Wnt signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

BMS-663069

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