DAX1/NR0B1 Antibody Summary
Synthetic 19 amino acid peptide from ligand-binding domain of human DAX1.
ligand-binding domain of human
Human DAX1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Monkey (100%), Primate (95%). Backed by our 100% Guarantee.
IgG
Polyclonal
Rabbit
NR0B1
Immunogen affinity purified
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Applications/Dilutions
- Immunohistochemistry-Paraffin 10 ug/ml
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Chimpanzee (100%), Gorilla (100%), Orangutan (100%), Gibbon (100%), Marmoset (95%), Rabbit (84%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS
0.1% Sodium Azide
1 mg/ml
Immunogen affinity purified
Alternate Names for DAX1/NR0B1 Antibody
- AHC
- AHCDSS
- AHCH
- AHX
- DAX1
- DAX1DAX-1
- dosage-sensitive sex reversal
- DSS-AHC critical region on the X chromosome protein 1
- GTD
- HHG
- NR0B1
- NROB1
- nuclear hormone receptor
- Nuclear receptor DAX-1
- nuclear receptor subfamily 0 group B member 1
- nuclear receptor subfamily 0, group B, member 1
Background
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.