Cysteinyl Leukotriene R1/CysLTR1 Antibody Summary

s12961-015-0043-6

Cysteinyl Leukotriene R1/CysLTR1 Antibody Summary

    Immunogen
    CYSLTR1 (AAH35750, 248 a.a. ~ 337 a.a) partial recombinant protein with GST tag.PYHIQRTIHLHFLHNETKPCDSVLTMQKSVVITLSLAASNCCFDPLLYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV
    Specificity
    CYSLTR1 – cysteinyl leukotriene receptor 1
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Mouse
    Gene
    CYSLTR1
    Purity
    Unpurified
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Applications/Dilutions

    Dilutions
        Western Blot 1:500
        ELISA
    Application Notes
    The quality control of this antibody is limited to Western blot on the immunizing protein. It has also been used for ELISA. Abnovas recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    50% Glycerol
    Preservative
    No Preservative
    Purity
    Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cysteinyl Leukotriene R1/CysLTR1 Antibody

      CysLT(1)
      CysLT1
      CYSLT1CysLT1
      CYSLT1R
      CYSLTR
      CysLTR1
      Cysteinyl leukotriene D4 receptor
      Cysteinyl Leukotriene R1
      cysteinyl leukotriene receptor 1
      Cysteinyl LeukotrieneR1
      G-protein coupled receptor HG55
      HG55
      HMTMF81
      LTD4 Receptor
      MGC46139

Background

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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