srep27114

Complement Component C1qA Antibody [FITC] Summary

    Immunogen
    C1QA isolated from the normal human serum.
    Specificity
    This reacts with human C1QA complement.all
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    C1QA
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        Immunocytochemistry/Immunofluorescence 1:20-1:40
    Positive Control C1q Lysate (NBL1-08337)

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

    Storage
    Store at 4C. Do not freeze.
    Buffer
    PBS
    Preservative
    0.05% Sodium Azide
    Purity
    IgG purified

Alternate Names for Complement Component C1qA Antibody [FITC]

      C1QA complement component 1, q subcomponent, A chain
      C1QA
      Complement Component C1qA

Background

C1q is a sub-component of the first complement component C1, which is formed by the interaction of C1q with the tetramer C1s-C1r-C1r-C1s.C1q is a member of a family of soluble collagen-like proteins and is composed of three basic subunits termed A, B and C (27,550, 25,200, 23,800 Da respectively) which asociate in the proportion 6 A-B subunits (52, 750 Da) and 3 C-C subunits (47,600 Da), to form whole C1q (459,300 Da). C1q binds to IgG and IgM immune complexes, this activates C1r and C1s, which are also bound to C1q and so initiates the classical pathway of complement activation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

MLi-13

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