Complement C3 Antibody Summary
Complement C3 native protein, sequence 1-1663 (NP_000055.1).
Secreted
C3
Polyclonal
Chicken
C3
Immunogen affinity purified
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Applications/Dilutions
- Western Blot 1:100-1:2000
- ELISA 1:100-1:2000
Reactivity Notes
Human.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS
0.02% Sodium Azide
1.49 mg/ml
Immunogen affinity purified
Alternate Names for Complement C3 Antibody
- AHUS5
- ARMD9
- ASP
- C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
- complement C3
- complement component 3
- complement component C3
- CPAMD1acylation-stimulating protein cleavage product
Background
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets : IFNAR inhibitors