Coagulation Factor III/Tissue Factor Antibody (CLB/TF-1) [DyLight 405] Summary
Made to Human CD142
NB100-64304 recognizes human CD142, a 45kD cell surface glycoprotein which is otherwise known as Tissue Factor (TF). CD142 expression can be induced on monocytes, macrophages and endothelial cells by various stimuli including interleukin 1, tumour necrosis factor and endotoxin. CD142 initiates the blood clotting cascade by binding coagulation factor VIIa, which activates factor IX or factor X by specific limited proteolysis. CD142 also plays an important role in inflammation, angiogenesis, and the pathophysiology of atherosclerosis and cancer.
IgG1
Monoclonal
Mouse
F3
Protein A purified
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Applications/Dilutions
- ELISA
- Flow Cytometry
Optimal dilution of this antibody should be experimentally determined.
Reactivity Notes
Reacts with Human.
Packaging, Storage & Formulations
Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Protein A purified
Notes
Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Alternate Names for Coagulation Factor III/Tissue Factor Antibody (CLB/TF-1) [DyLight 405]
- CD142 antigen
- CD142
- coagulation factor III (thromboplastin, tissue factor)
- Coagulation Factor III
- F3
- FLJ17960
- TF
- TFA
- Thromboplastin
- Tissue Factor
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.