Ceramide Kinase Antibody Summary
Synthetic 20 amino acid peptide from N-terminal extracellular domain of human CERK.
N-terminal extracellular domain of human
Human CERK. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Monkey (90%), Primate (90%). Backed by our 100% Guarantee.
IgG
Polyclonal
Rabbit
CERK
Immunogen affinity purified
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Applications/Dilutions
- Immunohistochemistry-Paraffin 20 ug/ml
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (90%), Gibbon (90%), Marmoset (90%), Canine (85%), Panda (85%), Bovine (80%), Elephant (80%), Rabbit (80%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS
0.1% Sodium Azide
1.0 mg/ml
Immunogen affinity purified
Alternate Names for Ceramide Kinase Antibody
- ceramide kinase
- dA59H18.2
- DKFZp434E0211
- EC 2.7.1.138
- FLJ21430
- FLJ23239
- hCERKLipid kinase 4
- KIAA1646dA59H18.3
- lipid kinase LK4
- LK4Acylsphingosine kinase
- MGC131878
Background
CERK, which phosphorylates Cer to produce ceramide 1-phosphate (C1P), was initially described as a Ca2+-stimulated lipid kinase that copurified with brain synaptic vesicles. CERK activity has been reported in HL60 cells, mast cells, and neutrophils. CERK is involved in phagolysosome formation in polymorphonuclear leukocytes and also in liposome fusion. C1P has been reported to have mitogenic effects. More recently, C1P was found to induce arachidonic acid release and prostanoid synthesis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.