CX3CR1 Antibody (528728) [PerCP (Peridinin-chlorophyll Protein Complex)] Summary
E. coli-derived recombinant human CX3CR1
Met1-Thr31, Leu91-Lys103, Thr168-Thr195, Lys257-Leu273
Accession # NP_001328
Met1-Thr31, Leu91-Lys103, Thr168-Thr195, Lys257-Leu273
Accession # NP_001328
Detects human CX3CR1 in direct ELISAs.
N/A
IgG1
Monoclonal
Mouse
CX3CR1
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions
- Flow Cytometry 10 uL/10^6 cells
-
Flow1 publication
- 12 months from date of receipt, 2 to 8 °C as supplied.
FAB5204C in the following applications:
Packaging, Storage & Formulations
Protect from light. Do not freeze.
Supplied in a saline solution containing BSA and Sodium Azide.
Sodium Azide
Protein A or G purified from hybridoma culture supernatant
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CX3CR1 Antibody (528728) [PerCP (Peridinin-chlorophyll Protein Complex)]
- Beta chemokine receptor-like 1
- CCRL1
- chemokine (C-C) receptor-like 1
- chemokine (C-X3-C motif) receptor 1
- chemokine (C-X3-C) receptor 1
- CMKbRL1
- CMK-BRL1
- CMK-BRL-1
- CMKDR1
- CX3C chemokine receptor 1
- CX3CR1
- Fractalkine receptor
- G protein-coupled receptor 13
- GPR13G-protein coupled receptor 13
- GPRV28
- V28
- V28C-X3-C CKR-1
Background
CX3CR1 is a 40 kDa seven transmembrane chemokine receptor that is expressed on several T cell subsets, monocytes, macrophages, microglia, and epithelial cells. CX3CR1 binding to membrane bound or soluble CX3CR1/Fractalkine promotes inflammatory responses by inducing monocyte adhesion to endothelial cells and macrophage activation. CX3CR1 polymorphisms are associated with the development of chronic inflammatory disorders. Alternately spliced isoforms have extended N-terminal extracellular regions that increase the potency of CX3CR1 as a fusion co-receptor for HIV-1. Human CX3CR1 shares 82% amino acid sequence identity with mouse and rat CX3CR1.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.