CRY1 Blocking Peptide Summary
A peptide corresponding to amino acids from the N-terminal region of human CRY1. Accession #: NP_004066.
Source: Synthetic
Amino Acid Sequence:
Synthetic
Blocking Peptide
CRY1
N/A
Applications/Dilutions
64 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
Lyophilized with sterile distilled water.
No Preservative
LYOPH
N/A
Add 100ul of sterile PBS. Final peptide concentration will be 1 mg/ml in PBS.
Notes
For longer periods of storage, aliquot and store at -20C. Avoid repeat freeze-thaw cycles.
Alternate Names for CRY1 Blocking Peptide
- CRY1
- cryptochrome 1 (photolyase-like)
- Cryptochrome I
- PHLL1
- PHLL1cryptochrome-1
- photolyase-like cryptochrome 1
Background
CRY1 is the blue light-dependent regulator of the circadian feedback loop. CRY1 inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription.CRY1 acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. CRY1 has no photolyase activity. CRY1 is capable of translocating circadian clock core proteins such as PER proteins to the nucleus. CRY1 may inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
product targets :　Stem_Cell_Signaling_Compound_Library inhibitors