journal.pone.0154606

CEACAM7 Antibody (934660) [Alexa Fluor® 350] Summary

    Immunogen
    E. coli-derived recombinant human CEACAM-7
    Asn37-Phe142
    Accession # Q14002
    Specificity
    Detects human CEACAM-7 in direct ELISAs. Stains human CEACAM-7 transfected cells but not irrelevant transfectants.
    Isotype
    IgG1
    Clonality
    Monoclonal
    Host
    Mouse
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Applications/Dilutions

    Dilutions
        Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

    Storage
    Store the unopened product at 2 – 8 °C. Do not use past expiration date.
    Buffer
    Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CEACAM7 Antibody (934660) [Alexa Fluor® 350]

      Carcinoembryonic antigen CGM 2
      Carcinoembryonic antigen CGM2
      Carcinoembryonic antigen gene family member 2
      Carcinoembryonic antigen related cell adhesion molecule 7
      CEA
      CEACAM 7
      CEACAM7
      CEACAM-7
      CGM 2
      CGM2

Background

CEACAM-7 (carcinoembryonic antigen cell adhesion molecule 7; also CGM2) is a 40‑45 kDa member of the CEACAM subfamily of the CEA family of proteins. It has a restricted expression pattern, being found on epithelium of the colon, appendix and pancreatic ducts. It is markedly down‑regulated in colon carcinoma. Mature human CEACAM-7 is a 209 amino acid (aa), GPI-linked glycoprotein. It contains one V-type (aa 36‑142) and one C2-type (aa 146‑233) Ig-like domain, plus a 21 aa C‑terminal propeptide. One alternate splice form exists that shows a deletion of aa 143‑235.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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