CD82/Kai-1 Antibody (B-L2) Summary

2333393615614300

CD82/Kai-1 Antibody (B-L2) Summary

    Immunogen
    Human CD82 transfected murine mastocytoma cell line P815
    Localization
    Integral membrane protein
    Specificity
    recognises the human CD82 antigen, a 50-53kD cell surface protein.
    Isotype
    IgG1
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    CD82
    Purity
    Protein A or G purified
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Applications/Dilutions

    Dilutions
        Flow Cytometry 1:10-1:1000
    Application Notes
    Flow Cytometry Use 10ul of the neat antibody to label 10<sup>6</sup> cells. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
    Positive Control CD82/Kai-1 Lysate (NBL1-08974)

Reactivity Notes

Not yet tested in other species.

Packaging, Storage & Formulations

    Storage
    Store at 4C. Do not freeze.
    Buffer
    PBS (pH 7.4) and 1.0% BSA
    Preservative
    0.1% Sodium Azide
    Purity
    Protein A or G purified

Alternate Names for CD82/Kai-1 Antibody (B-L2)

      CD82 antigenC33
      CD82 molecule
      CD82
      IA4
      IA4C33 antigen
      Inducible membrane protein R2
      KAI1
      KAI1GR15
      kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyteantigen, antigen detected by monoclonal and IA4))
      Metastasis suppressor Kangai-1
      R2
      SAR2
      SAR2tetraspanin-27
      ST6
      ST6tspan-27
      Suppressor of tumorigenicity 6 protein
      Tetraspanin-27
      TSPAN27
      Tspan-27
      TSPAN274F9

Background

CD82, a member of the tetraspanin (TM4SF) family, is a suppressor of tumorigenicity 6 and of metastasis in prostate, pancreatic, hepatocellular, cervical and colorectal carcinomas. It is expressed by T cells, NK cells, monocytes, granulocytes and platelets. CD82 associates with CD4 or CD8 and delivers co-stimulatory signals for the TCR/CD3 pathway

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : Integrin inhibitors