CD58/LFA-3 Antibody (L180/1) Summary
Sheep erythrocytes
Recognizes the ovine CD58 cell surface antigen, a 42kD glycoprotein also known as LFA-3. This blocks the binding of sheep red blood cells to both human and sheep T lymphocytes.
IgG1
Monoclonal
Mouse
CD58
Protein G purified
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Applications/Dilutions
- Flow Cytometry 1:10-1:25
- Immunoprecipitation 1:10-1:500
Reactivity Notes
Reacts with Sheep.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
No buffer
0.09% Sodium Azide
1.0 mg/ml
Protein G purified
Alternate Names for CD58/LFA-3 Antibody (L180/1)
- Ag3
- CD58 antigen
- CD58 antigen, (lymphocyte function-associated antigen 3)
- CD58 molecule
- CD58
- FLJ23181
- FLJ43722
- LFA3
- LFA-3
- LFA3ag3
- lymphocyte function-associated antigen 3
- Surface glycoprotein LFA-3
Background
LFA3 is a type 1 transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed on most hematopoietic cells and on nonhematopoietic cells such as fibroblasts, endothelial and epithelial cells. Its expression is particularly high on memory T-cells and dendritic cells. LFA3 expression on antigen-presenting cells and target cells enhances T-cells antigen recognition through binding to its ligand, LFA2/CD2, on T-cells.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.