CD4 Antibody (RPA-T4) [PE] Summary
Human PHA blasts
NB100-64882 recognizes human CD4, a 55kD cell surface glycoprotein that is primarily expressed on a subpopulation of T lymphocytes, on peripheral blood monocytes and on tissue macrophages. Epitope mapping studies have shown that antibodies, produced by clone RPA-T4, recognize an epitope within domain 1, of the extracellular region, of the CD4 molecule. Clone RPA-T4 has been reported to block gp120-CD4 interaction and inhibit syncytium formation.
IgG1
Monoclonal
Mouse
CD4
Protein A or G purified
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Applications/Dilutions
- Flow Cytometry 1:10-1:1000
Reactivity Notes
Reacts with Human.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS, 1.0% BSA, and 5% Sucrose
0.05% Sodium Azide
Protein A or G purified
Alternate Names for CD4 Antibody (RPA-T4) [PE]
- CD4 antigen (p55)
- CD4 antigen
- CD4 molecule
- CD4 receptor
- CD4
- CD4mut
- T-cell surface antigen T4/Leu-3
- T-cell surface glycoprotein CD4
Background
CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes (“helper/inducer” T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets :　Histone_Modification_Research_Compound_Library inhibitors