CD200 R1 Antibody (OX-110) [Biotin] Summary
Fusion protein mCD200RCD4d3+4
Isoform 1 and isoform 4: Cell membrane; single pass type I membrane protein. Isoform 2 and isoform 3: Secreted protein.
NB100-63562 recognizes mouse CD200R, a cell surface glycoprotein (also known as OX2R), In mouse CD200R is expressed primarily by peripheral blood monocytes and neutrophils but also by other leucocytes including T-lymphocytes and mast cells (1). Studies suggest that CD200-CD200R interaction may be involved in the control of myeloid cellular function.
IgG2a
Monoclonal
Rat
CD200R1
Protein G purified
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Applications/Dilutions
- Flow Cytometry 1:10-1:1000
- Streptavidin Full length Protein
- Streptavidin Native Protein
- Streptavidin Native Protein
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.4) and 1.0% BSA
0.09% Sodium Azide
0.1 mg/ml
Protein G purified
Alternate Names for CD200 R1 Antibody (OX-110) [Biotin]
- CD200 R1
- CD200 receptor 1
- CD200R1
- CD200RMOX2Rcell surface glycoprotein CD200 receptor 1
- Cell surface glycoprotein OX2 receptor 1
- cell surface glycoprotein receptor CD200
- CRTR2
- HCRTR2
- MOX2 receptor
- MOX2R
- OX2RCD200 cell surface glycoprotein receptor
Background
CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. It is a monomorphic determinant expressed on thymocytes, brain, follicular dendritic cells in all lymphoid organs, endothelium and at low levels on some smooth muscle and B lymphocytes. Recent studies have suggested that the CD200 – CD200 ligand system is of importance in the control of macrophage and granulocyte activation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.