aob/mcw025

CD19 Antibody (4G7-2E3R) [Alexa Fluor® 647] Summary

    Additional Information
    Recombinant Monoclonal Antibody.
    Immunogen
    Human CCL cells
    Specificity
    Detects human CD19.
    Isotype
    IgG1
    Clonality
    Monoclonal
    Host
    Mouse
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Applications/Dilutions

    Dilutions
        Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

    Storage
    Store the unopened product at 2 – 8 °C. Do not use past expiration date.
    Buffer
    Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD19 Antibody (4G7-2E3R) [Alexa Fluor® 647]

      B4
      B-lymphocyte antigen CD19
      B-lymphocyte surface antigen B4
      CD19 antigen
      CD19 molecule
      CD19
      CVID3
      Differentiation antigen CD19
      Leu-12
      MGC12802
      T-cell surface antigen Leu-12

Background

CD19 is a 95 kDa transmembrane glycoprotein with two Ig-like C2-set domains. CD19 regulates B cell development and activation through interactions with CD21, CD22, and the B cell receptor. CD19 polymorphisms and up‑regulation lead to the development of autoimmunity by promoting autoantibody production. Within the extracellular domain, human CD19 (Accession # P15391) shares 57% amino acid sequence identity with mouse and rat CD19.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : Src inhibitors

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