1932296816639310

CD16/CD32 Antibody (AP-MAB0815) Summary

    Immunogen
    Mouse Macrophagess
    Specificity
    The was selected for its ability to detect mouse natural killer cells, monocytes, macrophages, dendritic cells (at low levels), Kupffer cells, granulocytes, mast cells, B lymphocytes, immature thymocytes, and some activated mature T lymphocytes.
    Isotype
    IgG2
    Clonality
    Monoclonal
    Host
    Rat
    Gene
    FCGR3A
    Purity
    Protein A or G purified
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Applications/Dilutions

    Dilutions
        Blocking/Neutralizing 50-200 molar excess

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    A 0.2 um filtered solution in PBS – Azide free
    Preservative
    No Preservative
    Concentration
    1.0 mg/ml
    Purity
    Protein A or G purified

Alternate Names for CD16/CD32 Antibody (AP-MAB0815)

      CD16
      CD16A
      Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
      FCG3
      FCGR3
      FCGR3A
      FCGRIII
      FCR-10
      FCRIII
      FCRIIIA
      IGFR3

Background

CD16 is the low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses. This antibody is specific to the common epitope of CD16/CD32. It is useful for blocking non-specific binding of immunoglobulin to the Fc receptors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : Autophagy_Compound_Library inhibitors

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