CD16/CD32 Antibody (AP-MAB0815) Summary
Mouse Macrophagess
The was selected for its ability to detect mouse natural killer cells, monocytes, macrophages, dendritic cells (at low levels), Kupffer cells, granulocytes, mast cells, B lymphocytes, immature thymocytes, and some activated mature T lymphocytes.
IgG2
Monoclonal
Rat
FCGR3A
Protein A or G purified
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Applications/Dilutions
- Blocking/Neutralizing 50-200 molar excess
Reactivity Notes
Mouse.
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
A 0.2 um filtered solution in PBS – Azide free
No Preservative
1.0 mg/ml
Protein A or G purified
Alternate Names for CD16/CD32 Antibody (AP-MAB0815)
- CD16
- CD16A
- Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
- FCG3
- FCGR3
- FCGR3A
- FCGRIII
- FCR-10
- FCRIII
- FCRIIIA
- IGFR3
Background
CD16 is the low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses. This antibody is specific to the common epitope of CD16/CD32. It is useful for blocking non-specific binding of immunoglobulin to the Fc receptors.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets : Autophagy_Compound_Library inhibitors