CD161/NK1.1 Antibody (PK136) [Alexa Fluor® 700] Summary
Mouse NK-1+ splenocytes and bone marrow cells
Detects mouse CD161/NK1.1 by flow cytometry
N/A
IgG2a
Monoclonal
Mouse
KLRB1C
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions
- Flow Cytometry 5 uL/10^6 cells
Packaging, Storage & Formulations
- 12 months from date of receipt, 2 to 8 °C as supplied.
Protect from light. Do not freeze.
Supplied in a saline solution containing BSA and Sodium Azide.
Sodium Azide
Protein A or G purified from hybridoma culture supernatant
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CD161/NK1.1 Antibody (PK136) [Alexa Fluor® 700]
- CD161 antigen
- CD161
- CD161/NK1.1
- CD161c
- CLEC5BC-type lectin domain family 5 member B
- HNKR-P1a
- killer cell lectin-like receptor subfamily B member 1
- killer cell lectin-like receptor subfamily B, member 1
- Klrb1c
- Ly55c
- Ly-59
- Natural killer cell surface protein P1A
- NKR-P1
- NKR-P1AMGC138614
- NKRP1ANKR
Background
CD161, also known as NK1.1, KLRB-1C, Ly-55, and NKR-P1c, is a 28 kDa type 2 transmembrane protein in the Killer Cell Lectin-like Receptor family. CD161 is expressed as a disulfide-linked homodimer on the surface of NK cells and subpopulations of NKT, CD4+, CD8+, and gamma /δ T cells. Its cross-linking on NK cells induces cytolytic activity, and on CD4 cells it promotes IgE production and the expansion of Th2 responses. Mature mouse CD161 consists of a 45 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 157 aa extracellular domain with one C-type lectin domain.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.