CD117/c-kit Antibody (kit2c75) Summary
Sp/chkit4A4 cells (Sp2/0 cells transfected with chicken c-Kit cDNA)
Hematopoietic Stem Cell Marker
Chicken c-Kit
IgG2a Kappa
Monoclonal
Mouse
KIT
Protein A or G purified
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Applications/Dilutions
- Flow Cytometry <= 1 ug/10^6 cells
- Immunocytochemistry/Immunofluorescence
ICC,IF reactivity reported in scientific literature (PMID: 9714410).
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
0.1M BBS (pH 8.2)
No Preservative
0.5 mg/ml
Protein A or G purified
Alternate Names for CD117/c-kit Antibody (kit2c75)
- CD117 antigen
- CD117
- ckit
- c-kit
- EC 2.7.10
- EC 2.7.10.1
- KIT
- PBT
- piebald trait
- Proto-oncogene c-Kit
- proto-oncogene tyrosine-protein kinase Kit
- SCF R
- SCFR
- SCFRmast/stem cell growth factor receptor
- soluble KIT variant 1
- Tyrosine-protein kinase Kit
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
Background
c-Kit is a 145 kDa transmembrane receptor-type protein tyrosine kinase encoded by the c-Kit protooncogene and is the receptor for stem cell factor (SCF). 1 c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. 2, 3, 4, 5 The amino acid sequence of chicken c-kit shows 63% identity to mouse c-Kit and exhibits similar expression patterns in RNA blot analysis suggesting similar biological roles. (1)
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.