CCL2/MCP1 Antibody (24822) Summary
Recombinant human MCP-1/CCL2 expressed in E. coli.
Secreted
The will neutralize the biological activity of recombinant human MCP-1.This does not exhibit cross-reactivity with recombinant human RANTES, recombinant human MIP-1 alpha, or recombinant mouse MIP-1 alpha
IgG1
Monoclonal
Mouse
CCL2
Protein A purified
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Applications/Dilutions
- Western Blot 1:100-1:2000
- Blocking/Neutralizing 50-200 molar excess
- ELISA 1:100-1:2000
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
PBS and 5% Trehalose
No Preservative
0.5 mg/ml
Protein A purified
Alternate Names for CCL2/MCP1 Antibody (24822)
- C-C motif chemokine 2
- chemokine (C-C motif) ligand 2
- GDCF-2
- HC11Monocyte secretory protein JE
- MCAFMonocyte chemotactic and activating factor
- MCP1 Monocyte chemotactic protein 1
- MCP-1 Small-inducible cytokine A2
- MGC9434
- Monocyte chemoattractant protein 1
- monocyte chemoattractant protein-1
- SCYA2HSMCR30
- small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je)
- small inducible cytokine subfamily A (Cys-Cys), member 2
- SMC-CF
Background
This chemotactic factor attracts monocytes and basophils but not neutrophils or eosinophils and augments monocyte anti-tumor activity. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. It may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets :　Mixed Lineage Kinase inhibitors