Bone marrow stromal cell antigen 1/CD157 Antibody (534509) [Alexa Fluor® 594] Summary
NS0 mouse myeloma cell line transfected with human CD157
Gly29-Lys292
Accession # Q10588
Gly29-Lys292
Accession # Q10588
Detects human CD157 in direct ELISAs.
IgG1
Monoclonal
Mouse
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Applications/Dilutions
- Flow Cytometry 0.25-1 ug/10^6 cells
Packaging, Storage & Formulations
Store the unopened product at 2 – 8 °C. Do not use past expiration date.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Bone marrow stromal cell antigen 1/CD157 Antibody (534509) [Alexa Fluor® 594]
- ADP-ribosyl cyclase 2
- Bone marrow stromal antigen 1
- bone marrow stromal cell antigen 1
- BP-3
- BST1
- BST-1
- cADPr hydrolase 2
- CD157 antigen
- CD157
- Cyclic ADP-ribose hydrolase 2
- EC 3.2.2.5
- NAD(+) nucleosidase
Background
CD157, also known as Bone Marrow Stromal Cell Antigen 1 (BST-1), is a glycosyl phosphatidylinositol anchored membrane protein that belongs to the CD38 family (1). CD157 was discovered in a bone marrow stromal cell line where it facilitates pre-B-cell growth (2, 3). Along with CD38, CD157 is a bifunctional ectoenzyme that exhibits both ADP-ribosyl cyclase and cyclic ADP ribose hydrolase activities (2). It may play a role in rheumatoid arthritis (RA) due to its enhanced expression in
RA-derived bone marrow stromal cell lines (3). CD157 has been predicted to function as a cell surface receptor and an immunoregulatory molecule (4).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.