Bestrophin 3 Antibody Summary
Synthetic 20 amino acid peptide from internal region of human BEST3.
near N-terminal domain of human
Human BEST3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Porcine (90%), Bovine (90%), Hamster (90%), Bat (95%), Monkey (100%), Primate (95%). Backed by our 100% Guarantee.
IgG
Polyclonal
Rabbit
BEST3
Immunogen affinity purified
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Applications/Dilutions
- Immunohistochemistry-Paraffin 1:10 – 1:500
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (95%), Elephant (90%), Panda (90%), Canine (85%), Rabbit (85%), Mouse (80%), Rat (80%), Equine (80%), Platypus (80%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS
0.1% Sodium Azide
1.0 mg/ml
Immunogen affinity purified
Alternate Names for Bestrophin 3 Antibody
- bestrophin 3
- bestrophin-3
- MGC13168
- MGC40411
- vitelliform macular dystrophy 2-like 3
- VMD2L3Vitelliform macular dystrophy 2-like protein 3
Background
VMD2L3, a bestrophin, is an anion channel. The VMD2 gene underlying vitelliform macular dystrophy and the 3 VMD2-like genes, VMD2L1, VMD2L2, and VMD2L3, encode transmembrane (TM) spanning proteins that share a homology region with a high content of aromatic residues including an invariant arginine (R), phenylalanine (F), and proline (P) motif. VMD2 and the 3 VMD2-related genes share a conserved gene structure with almost identical sizes of the 8 RFP-TM domain encoding exons and highly conserved positions of their corresponding exon-intron boundaries. Each of the 4 paralogous genes contains a unique 3-prime end of variable length without significant homology to known proteins or motifs.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.