nrp.2016.10.1.49

BRS3 Antibody Summary

    Immunogen
    Synthetic 13 amino acid peptide from C-terminus of human BRS3.
    Specificity
    Human BRS3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Predicted Species
    Primate (92%), Monkey (92%). Backed by our 100% Guarantee.
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    BRS3
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        Immunohistochemistry-Paraffin 3 – 17 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (92%).

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    PBS
    Preservative
    0.1% Sodium Azide
    Concentration
    1.0 mg/ml
    Purity
    Immunogen affinity purified

Alternate Names for BRS3 Antibody

      BB3
      bombesin receptor subtype 3
      bombesin receptor subtype-3
      bombesin-like receptor 3
      BRS3
      BRS-3
      G-protein coupled receptor

Background

BRS3 is classified as an Orphan-A Receptor and is highly similar to the bombesin receptors but has a very low affinity for bombesin itself. Mice lacking BRS3 develop metabolic defects and obesity, suggesting that BRS3 may be an important target for obesity research. In addition, BRS3 may be involved in diabetes and hypertension. BRS3 expression has been reported in lung (normal and cancer), nasal mucosa, placenta, and uterus. ESTs have been isolated from normal brain and kidney cancer libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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