s12978-017-0322-5

BRDG1/STAP-1 Antibody Summary

    Immunogen
    Peptide with the sequence GRSEKLKKNPHIA from the C terminus of the protein.Sequence according to the Entrez Gene accession number NP_036240
    Specificity
    BRDG1
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Goat
    Gene
    STAP1
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        Western Blot 1:100-1:2000
    Positive Control BRDG1/STAP-1 Lysate (NBL1-16514)

Reactivity Notes

Reacts with Human.

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    TBS and 0.5% BSA
    Preservative
    0.02% Sodium Azide
    Concentration
    0.5 mg/ml
    Purity
    IgG purified

Alternate Names for BRDG1/STAP-1 Antibody

      BCR downstream-signaling protein 1
      BRDG1
      BRDG1STAP-1BCR downstream signaling 1
      Docking protein BRDG1
      signal transducing adaptor family member 1
      signal-transducing adaptor protein 1
      signal-transducing adaptor protein-1
      STAP1
      Stem cell adaptor protein 1

Background

BRDG 1 functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a positive feedback loop, increasing Tec activity. A mouse ortholog, stem cell adapter protein 1, shares 83% identity with its human counterpart.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Lodoxamide (tromethamine)

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