reg2.48

Aldehyde Dehydrogenase 1-A1/ALDH1A1 Antibody (1A2) Summary

    Immunogen
    ALDH1A1 (AAH01505, 1 a.a. – 110 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSSSGTPDLPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMN
    Marker
    Astrocyte Marker
    Specificity
    ALDH1A1 – aldehyde dehydrogenase 1 family, member A1
    Isotype
    IgG2b Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    ALDH1A1
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        ELISA
    Application Notes
    Antibody reactivity against recombinant protein on ELISA.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    PBS (pH 7.4)
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Aldehyde Dehydrogenase 1-A1/ALDH1A1 Antibody (1A2)

      acetaldehyde dehydrogenase 1
      ALDC
      aldehyde dehydrogenase 1 family, member A1
      aldehyde dehydrogenase 1, soluble
      Aldehyde Dehydrogenase 1A1
      Aldehyde Dehydrogenase 1-A1
      Aldehyde dehydrogenase family 1 member A1
      Aldehyde dehydrogenase, cytosolic
      aldehyde dehydrogenase, liver cytosolic
      ALDH class 1
      ALDH1
      ALDH11
      ALDH1A1
      ALDH-E1
      ALHDII
      EC 1.2.1
      EC 1.2.1.36
      MGC2318
      PUMB1
      RALDH 1
      RALDH1
      retinal dehydrogenase 1
      retinaldehyde dehydrogenase 1

Background

This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

SAR245410

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