biom5042723

Aconitase 2 Antibody (1A11) Summary

    Immunogen
    ACO2 (AAH14092, 1 a.a. – 179 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEYIHYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQFISSGLSKVAVPSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWKPGSGIIHQIILE
    Specificity
    aconitase 2, mitochondrial
    Isotype
    IgG2a Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    ACO2
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        ELISA
    Application Notes
    Antibody reactivity against recombinant protein on ELISA.
    Publications Read Publication using H00000050-M01.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    PBS (pH 7.4)
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Aconitase 2 Antibody (1A11)

      aconitase 2, mitochondrial
      Aconitase
      aconitate hydratase, mitochondrial
      ACONM
      Citrate hydro-lyase
      EC 4.2.1
      EC 4.2.1.3
      MGC20605
      MGC33908

Background

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : Melatonin Receptor inhibitors

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