APP Blocking Peptide Summary
15 amino acids near the carboxy terminus of human APP. Accession #: CAA30050.
Source: Synthetic
Blocking Peptide
APP
N/A
Applications/Dilutions
Can be used to block the binding of NBP1-76910
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
0.02% Sodium Azide
0.2 mg/ml
N/A
Alternate Names for APP Blocking Peptide
- amyloid beta (A4) precursor protein-binding, family B, member 2
- amyloid beta A4 precursor protein-binding family B member 2
- Amyloid beta precursor protein
- Amyloid beta
- APP
- beta Amyloid
- Protease Nexin II
Background
A large body of evidence has implicated the amyloid precursor protein (APP) in the pathogenesis of Alzheimers disease (AD). The phosphorylation APP at Thr668 is thought to play a critical role in generation of the soluble APP (beta) and beta-amyloid peptide (abeta) which are the major components of senile plaques in patient brains inflicted with AD.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
product targets :　Opioid Receptor inhibitors