s13054-015-1028-0

ALK-1 Antibody (5F2) Summary

    Immunogen
    ACVRL1 (AAH42637, 22 a.a. – 119 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. DPVKPSRGPLVTCTCESPHCKGPTCRGAWCTVVLVREEGRHPQEHRGCGNLHRELCRGRPTEFVNHYCCDSHLCNHNVSLVLEATQPPSEQPGTDGQL
    Specificity
    ACVRL1 – activin A receptor type II-like 1
    Isotype
    IgG1 Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    ACVRL1
    Purity
    IgG purified
    Innovators Reward
    Test in a species/application not listed above to receive a full credit towards a future purchase.

    Learn about the Innovators Reward

Applications/Dilutions

    Dilutions
        Western Blot
        ELISA
    Application Notes
    Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    PBS (pH 7.4)
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ALK-1 Antibody (5F2)

      activin A receptor type II-like 1
      activin A receptor, type II-like kinase 1
      Activin receptor-like kinase 1
      ACVRL1
      ACVRLK1ORW2
      ALK1
      ALK-1
      ALK1TGF-B superfamily receptor type I
      EC 2.7.11
      HHT
      HHT2EC 2.7.11.30
      serine/threonine-protein kinase receptor R3
      SKR3
      TSR-I

Background

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

LY2157301

Related Post